The Spitzer Space Telescope (formerly SIRTF), the infrared component of NASA's series of Great Observatories, was launched on August 25, 2003. The Spitzer Science Center is located within IPAC, and the Spitzer Heritage Archive is hosted by IRSA.

The NASA Exoplanet Science Institute (NExScI) provides tools and archives for the exoplanet community, administers the Sagan program of fellowships and workshops, supports the Keck Interferometer and Large Binocular Telescope Interferometer. NExScI provides administration of NASA Keck telescope time, and additional projects in the Exoplanet Exploration Program.

The Cube Builder for IRS Spectra Maps, is a tool for constructing spectral cubes, maps, and arbitrary aperture 1D spectral extractions from sets of mapping mode spectra taken with Spitzer's IRS spectrograph.

Finder Chart provides image cutouts from the 2MASS, SDSS, and DSS sky surveys around a user specified location, allowing comparisons across wavelengths and time.

Scanpi is an interactive software tool for viewing, plotting and averaging the calibrated survey scans from the Infrared Astronomical Satellite (IRAS); these scans are the fundamental data from the IRAS survey.

IRSCLEAN is an interactive IDL tool for creating bad pixel masks from Spitzer IRS BCD (and pre-BCD) image data, and "cleaning" the masked pixels in a set of data.

MOPEX (MOsaicker and Point source EXtractor) is a package for reducing and analyzing imaging data, as well as MIPS SED data. MOPEX includes the point source extraction package, APEX.

The Customizable User Pipeline for IRS Data (CUPID) allows users to run the Spitzer IRS Pipelines to re-create Basic Calibrated Data and extract calibrated spectra from the archived raw files.

This service computes the interstellar reddening for a line of sight and/or region of the sky, returning the corresponding 100 μm intensity, reddening maps, region statistics, and estimated Galactic extinction.

IRSA provides a set of five IDL programs to assist users in working with catalogs and tables.

Montage is a toolkit for assembling Flexible Image Transport System (FITS) images into custom mosaics.

The Spitzer IRS Custom Extraction (SPICE) software is a JAVA-based tool to interactively extract Spitzer Infrared Spectrograph (IRS) spectra.